Historically, Afyonkarahisar has been a thermal center for people in benefiting from medicinal hot springs. Thanks to its rich mineral content and absence of biological pollution, thermal waters offer an efficient treatment. They have been observed to have positive impacts on the treatment of osteoarthritis (calcification), fibromyalgia, quiescent periods of inflammatory rheumatic diseases, soft tissue rheumatism, fracture sequelae, movement disorders and certain skin diseases.

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Afyon Kalesi